ACE-031: Myostatin Inhibition and Muscle Research
ACE-031 is a synthetic activin receptor type IIB (ActRIIB) ligand trap — a soluble decoy receptor studied for its ability to bind myostatin and related ligands before they can signal, effectively removing a key biological brake on muscle growth in research models.
What is ACE-031?
ACE-031 is a soluble form of the ActRIIB receptor. It acts as a decoy, binding myostatin, activin A, and related growth factors so they cannot engage their native receptors. Because myostatin normally restrains muscle growth, trapping it is studied as a route to increased muscle mass and strength in preclinical models.
Research areas
- Muscle-mass & strength models: investigating myostatin inhibition’s effect on skeletal-muscle hypertrophy.
- Sarcopenia research: age-related muscle-loss models exploring maintenance of muscle function.
- Cachexia research: muscle-wasting models associated with chronic-disease states.
- Muscular-dystrophy & performance research: exploratory work on muscle preservation and physical capacity.
Handling for Canadian research labs
- Not authorized by Health Canada for human use — laboratory research only.
- Store lyophilized at −20°C; reconstitute with sterile bacteriostatic water using aseptic technique.
- Source from reputable suppliers providing third-party purity testing and a COA.
Explore related recovery and tissue-research compounds we carry: TB-500, BPC-157, and the GH-secretagogue Ipamorelin — all third-party tested to over 99% purity with a COA. Pair with bacteriostatic water for reconstitution.
This guide is part of our Peptides Canada research hub — explore the full library of compound guides.
Disclaimer: Educational and research content only. ACE-031 is discussed strictly as a research chemical, not for human consumption or therapeutic use. All work must comply with Canadian regulations and institutional ethics approvals.