Tesamorelin: The GHRH Analogue for Metabolic and Visceral Adipose Research
Tesamorelin (brand name Egrifta) is a synthetic 44-amino-acid analogue of Growth Hormone-Releasing Hormone (GHRH), engineered to resist enzymatic degradation for a more sustained effect. In research it is distinguished by its specific impact on visceral adipose tissue (VAT) — the deep fat around internal organs — making it a primary subject for metabolic-syndrome and lipodystrophy studies.
Mechanism: targeted lipolysis
- Pulsatile GH release: like CJC-1295 (No-DAC), triggers a natural pulsatile GH release that preserves endocrine rhythm.
- IGF-1 production: increased GH stimulates hepatic IGF-1, mediating growth/repair functions.
- Selective lipolysis: reduces visceral fat without significantly affecting subcutaneous fat — by increasing fat oxidation and inhibiting de novo lipogenesis.
Primary research focus areas
- HIV-associated lipodystrophy: the original, established research area (visceral fat accumulation on long-term antiretroviral therapy).
- Non-alcoholic fatty liver disease (NAFLD): investigated for reducing liver fat fraction and inflammation.
- Cognitive health: emerging GH-brain-axis studies on cognition/neuroplasticity in aging models.
Canadian regulatory status
- Authorized medication: unlike BPC-157 or TB-500, Tesamorelin (as Egrifta) is a Health Canada-approved drug — but strictly for HIV-associated lipodystrophy.
- Prescription only outside that use; not an OTC natural health product.
- Research chemicals: tesamorelin sold without prescription is a research chemical — “for research purposes only,” not for human consumption.
- WADA/CCES: prohibited in and out of competition (S2).
Lab handling & reconstitution
- Store lyophilized at −20°C; reconstitute with sterile/bacteriostatic water; stable ~24–48h refrigerated at 2–8°C.
- Precise micro-measurement required to avoid over-stimulating the pituitary.
Browse research-grade Tesamorelin — third-party tested to over 99% purity with a COA.
This guide is part of our Peptides Canada research hub — explore the full library of compound guides.
Note: Educational/research content only. Tesamorelin sold as a research peptide is not for human use.
Frequently Asked Questions
What is Tesamorelin: The GHRH Analogue for Metabolic and Visceral Adipose Research used for in research?
Tesamorelin: The GHRH Analogue for Metabolic and Visceral Adipose Research is studied in laboratory settings for its published biochemical pathways and signaling roles. Nuvion supplies it strictly for in-vitro and research use — not for human or veterinary consumption.
Are Nuvion peptides for human use?
No. All products are sold strictly for laboratory and research use only (RUO). They ship as sterile lyophilized powder for reconstitution per your lab protocol.
Does Nuvion ship within Canada and provide a COA?
Yes. Orders ship discreetly within Canada with tracking. Every batch includes third-party testing documentation; request the certificate of analysis for your lot from the product page or our COA directory.
